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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3A
All Species:
34.85
Human Site:
T574
Identified Species:
69.7
UniProt:
Q96ST3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ST3
NP_001138829.1
1273
145175
T574
Q
P
K
C
T
G
R
T
P
L
C
K
E
V
L
Chimpanzee
Pan troglodytes
XP_510682
1273
145185
T574
Q
P
K
C
T
G
R
T
P
L
C
K
E
V
L
Rhesus Macaque
Macaca mulatta
XP_001103539
1273
145217
T574
Q
P
K
C
T
G
R
T
P
L
C
K
E
V
L
Dog
Lupus familis
XP_535546
1240
141674
E573
S
S
K
K
T
Q
Y
E
E
H
I
Y
R
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60520
1282
146164
T575
Q
P
K
C
T
G
R
T
P
L
C
K
E
V
L
Rat
Rattus norvegicus
NP_001102231
1129
127784
L509
V
Q
L
V
S
P
F
L
G
K
F
P
E
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512119
1268
144524
T568
Q
P
K
C
T
G
R
T
P
L
C
K
E
V
L
Chicken
Gallus gallus
XP_413695
1272
145279
T573
Q
P
K
C
T
G
R
T
P
L
C
K
E
V
L
Frog
Xenopus laevis
NP_001081937
1275
145070
T576
Q
P
K
C
T
G
R
T
P
L
S
K
E
V
L
Zebra Danio
Brachydanio rerio
NP_001091650
1276
145765
T577
L
P
K
C
T
G
R
T
A
I
C
K
E
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
T601
Q
P
K
C
T
G
R
T
G
L
C
N
Q
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
D772
M
P
C
S
G
R
D
D
M
C
W
E
V
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.8
96.4
N.A.
97.4
86.8
N.A.
90.8
91.1
82.3
78
N.A.
N.A.
N.A.
N.A.
53
Protein Similarity:
100
99.9
99.8
96.9
N.A.
98.4
87.7
N.A.
94.9
94.9
89.5
86.9
N.A.
N.A.
N.A.
N.A.
67.5
P-Site Identity:
100
100
100
13.3
N.A.
100
6.6
N.A.
100
100
93.3
80
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
13.3
N.A.
100
20
N.A.
100
100
93.3
86.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
9
75
0
0
0
0
0
9
67
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
9
0
0
9
75
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% F
% Gly:
0
0
0
0
9
75
0
0
17
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
9
% I
% Lys:
0
0
84
9
0
0
0
0
0
9
0
67
0
0
0
% K
% Leu:
9
0
9
0
0
0
0
9
0
67
0
0
0
17
67
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
0
84
0
0
0
9
0
0
59
0
0
9
0
0
0
% P
% Gln:
67
9
0
0
0
9
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
9
75
0
0
0
0
0
9
0
0
% R
% Ser:
9
9
0
9
9
0
0
0
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
84
0
0
75
0
0
0
0
0
0
0
% T
% Val:
9
0
0
9
0
0
0
0
0
0
0
0
9
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _